Some factors that influence this include:. The higher the dose, the longer it takes for the body to metabolize the drug and for hydrocodone to leave the system. Younger people process hydrocodone more quickly than older adults. This is mostly because their organ systems are stronger and healthier, compared with the systems of adults. The quality and quantity of these enzymes vary from person to person according to their genes. This, too, can affect how a person metabolizes a drug.
When a person uses hydrocodone for a longer period — such as months or years — it likely takes longer to eliminate the drug from their system, compared with people who only take hydrocodone for a few days.
This effect is related to pharmacodynamic tolerance. To put it simply, higher doses of hydrocodone take longer to leave the body than lower doses that a person takes for a shorter time.
The American Addiction Centers also list symptoms that people who take hydrocodone report less frequently. These are:. Hydrocodone also has the potential to cause weak or shallow breathing, so people with asthma or a respiratory condition should check with their doctor about other forms of treatment. Hydrocodone is an addictive drug, so it is not uncommon for people to misuse it or consume more than the prescribed dose. One condition that can occur in people who misuse opioids, including hydrocodone, is narcotic bowel syndrome , in which the drug causes bowel function to slow.
If a person misuses hydrocodone by taking it via the nose, it can cause them to lose their sense of smell. Snorting the drug can also lead to nosebleeds, congestion, and frequent sinus infections. According to the National Center for Biotechnology Information , long term use of hydrocodone alongside acetaminophen increases the risk of liver damage and liver failure. The life of a drug is measured by its half-life, or how long it takes the body to metabolize half of the drug. For a standard 10mg dose of hydrocodone, the half-life is around 4 hours, meaning that it takes roughly 4 hours for the body to process and eliminate half the hydrocodone.
It takes several half-lives to fully eliminate the drug, but generally one dose of hydrocodone should be gone within 24 hours. You will stop feeling the effects of the hydrocodone before it fully leaves your body. Withdrawal symptoms usually begin anywhere from hours after the dose has been taken.
Dosage, frequency of use, and bodily heath all play a role in the timeline and the intensity of the withdrawal symptoms. Withdrawal symptoms are generally flu like symptoms, including: muscle aches, runny nose, nausea, vomiting, diarrhea, cramps, chills and sweats, irregular heart rate, difficulty concentrating, irritability, headaches, fatigue.
Symptoms can also be more severe such as seizures or spikes in blood pressure. It is important to be under supervised medical care when coming off of hydrocodone.
The process can be stressful and uncomfortable, or even painful, for someone who has developed a dependence on or addiction to hydrocodone. Medically supervised detox is recommended, and inpatient or outpatient treatment for hydrocodone addiction should also be used.
Withdrawal symptoms generally begin to improve within 72 hours, and are significantly better within one week. While the half-life is only a few hours, drug tests can still pick up traces of Vicodin for days.
For example, Vicodin shows up in a urine test up to four days after the previous dose. Using a hair test, labs can find traces of it up to 90 days after. With that said, it can take around ten days for Vicodin to show up in a hair test.
A saliva test is one of the easiest ways to check people for Vicodin use. However, it can only find traces of the drug between 12 and 36 hours of use. After that, this test can no longer detect Vicodin. When people determine how long does Vicodin stay in your system, they should keep a few things in mind. According to American Addiction Centers, no exact timeline fits everyone. Numerous factors affect how long the drug stays in their system after use.
For example, the larger the dose of Vicodin that people take, the longer it stays in their system. The reason is that hydrocodone builds up over time. Also, their level of hydration affects the timeline. The more water that they drink, the harder that it is to detect the drug in their urine. Although they are prescription drugs, opioids such as hydrocodone have been associated with serious health issues and have led to a series of overdoses and deaths across the nation.
In , more than 20, people died from opioid prescription-related overdoses in the United States, according to the American Society of Addiction Medicine. Read the information contained in the Medication Guide before you begin treatment with hydrocodone. Speak to your doctor if you have any questions or concerns.
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Health Conditions Discover Plan Connect. Medically reviewed by Alan Carter, Pharm. Time it takes to feel effects Time it takes to wear off Influencing factors Withdrawal symptoms Takeaway What is hydrocodone? When combined with acetaminophen or ibuprofen, hydrocodone goes by the brand names: Vicodin Lortab Lorcet Norco There are also several extended-release formulations of hydrocodone, including: Hysingla ER Zohydro ER Hydrocodone comes with many warnings due to its high potential for abuse and addiction.
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