Ezetimibe how does it work




















The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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Here are some natural ways to lower your triglycerides. Carrying high levels of LDL cholesterol in your blood ups the chance of heart attack and stroke. You want to do all you can to keep cholesterol levels…. Health Conditions Discover Plan Connect. Ezetimibe, Oral Tablet. Important warnings About Side effects Interactions Other warnings Dosage Take as directed Important considerations Alternatives Highlights for ezetimibe Ezetimibe oral tablet is available as a generic drug and a brand-name drug.

Brand name: Zetia. Ezetimibe comes only as a tablet you take by mouth. Ezetimibe oral tablet is used to reduce high cholesterol levels. Important warnings. What is ezetimibe? Ezetimibe side effects. Ezetimibe may interact with other medications. Ezetimibe warnings. How to take ezetimibe. Take as directed.

Taking ezetimibe by itself Ezetimibe is licensed to be used by itself if you have primary hypercholesterolaemia, which includes heterozygous FH as well as other conditions, and you can't take statins or they're not working for you.

Ezetimibe is not suitable during pregnancy or if you are breastfeeding. Like all medicines, ezetimibe can sometimes cause side effects. If you take ezetimibe by itself , any side effects are usually mild and temporary. These can include:. You can find a full list of reported side effects in the patient information leaflet which comes with your medication. Occasionally, side effects can be more serious, so tell your doctor if you experience anything unusual for you.

Talk to your doctor if you have questions about the risks and benefits of treating increased amounts of cholesterol in your blood with ezetimibe and other medications. In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your blood cholesterol levels. Ezetimibe comes as a tablet to take by mouth.

It is usually taken once a day with or without food. To help you remember to take ezetimibe, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Take ezetimibe exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Continue to take ezetimibe even if you feel well. Do not stop taking ezetimibe without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.

Do not take a double dose to make up for a missed one. Ezetimibe is a non-statin lipid-lowering medication that inhibits absorption of dietary cholesterol by blocking the Niemann-Pick C1-Like 1 protein NPC1L1. Moreover, based on a recent unique analysis of the IMPROVE-IT trial, ezetimibe reduced additional and total cardiovascular events over the course of the study, not only the first occurring event as trials are traditionally designed to assess.

The expert panel stated that non-statin therapies were an important consideration in high-risk patients when a less-than-anticipated LDL-C lowering was observed. Priority was placed on agents shown to provide net clinical benefit; however, questions lingered. How low can we go with LDL-C? Is ezetimibe safe? The analysis addresses the fact that patients with a nonfatal, first cardiovascular event are at risk of developing additional events.



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